Description
buy now at discount price!Rosmarinic acid CAS :20283-92-5
General description
Rosmarinic acid is a naturally occurring polyphenolic compound found in plants of the Boraginaceae family and Nepetoideae subfamily. It is an ester of caffeic acid as well as 3,4-dihydroxy-phenyllactic acid.[1]
Application
Rosmarinic acid has been used:
- to see its protective effects on the human endothelial cell line (EA.hy926) to treat diabetic atherosclerosis[2]
- to test its effect in 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) induced Parkinson′s disease (PD) models on attenuating inflammatory responses and microglia activation[3]
- to test its neuroprotective effects on dopaminergic neurons[4]
- to test its effects on sperm motility, viability and on intracellular calcium ion concentration[5]
- as a reference standard in capillary zone electrophoresis (CZE) method[6]
Biochem/physiol Actions
Rosmarinic acid (RosA) is a well-appreciated agent used in several diabetic conditions and complications such as diabetic nephropathy, diabetic neuropathy and diabetic atherosclerosis.[2] It has also been implicated to be a neuroprotective agent for several neurological disorders such as Alzheimer′s disease, Parkinson′s disease, and epilepsy by suppressing their conditions.[7][3][4]
About This Item
Empirical Formula (Hill Notation):
C18H16O8
CAS Number:
Molecular Weight:
360.31
Beilstein:
2227587
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.25
biological source
Rosemarinus officinalis L.
Assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white to faint beige
mp
171-175 °C (lit.)
solubility
H2O: 1 mg/mL, clear, colorless
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
SMILES string
OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2
InChI
1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1
InChI key
DOUMFZQKYFQNTF-WUTVXBCWSA-N
